Development of new knowledge, (bio-)technologies and products that enable valorisation of key biorefinery by-products


The Valor-Plus supports the realisation of sustainable, economically viable closed loop integrated biorefineries through the development of new knowledge, (bio-)technologies and products that enable valorisation of key biorefinery by-products. The project comprises five key areas:

  • Pre-treatment and fractionation.
  • Hemicellulose valorisation.
  • Lignin valorisation.
  • Glycerol valorisation.
  • Demonstration of the technological and economic potential for integration and scale-up within existing and future biorefinery value chains.


  •  Develop pretreatment processes for the recovery of cellulose, hemicellulose, lignin.
  • Develop an enzymatic process for the hydrolysis of hemicellulose to oligomers, sugars.
  • Develop processes for the fermentation of pentoses to butanol, microbial proteins.
  • Develop new chemical-enzymatic and chemical-microbiological processes for lignin depolymerization and transformation.
  • Develop fermentation processes to obtain added value products from glycerol.


  • New pretreatment processes for lignocellulosic biomass.
  • New processes for controlled hydrolysis of hemicellulose.
  • New chemical-microbiological and enzymatic processes for depolymerization and transformation of lignin.
  • New strains of yeasts and fungi for the fermentation of crude glycerol in lipids, organic acids and alcohols.
  • Review of the potential for the expansion and integration of project results within biorefineries.

Expected results

  • Pre-treatment: extrusion, ultrasound, dissolution, precipitation and filtration.
  • Hemicellulose valorization: enzymatic processes and chromatography, transformation into sugars and organic acids.
  • Lignin valorisation: chemical catalytic techniques for depolymerization, enzymatic and microbial processes to obtain added value products.
  • Glycerol valorisation: microbial engineering, fermentation and filtration to obtain lipids.


Video presenttion of the project:



Total budget: € 9 872 083,02
EC contribution: € 423 680
Duration: 01/12/2013 to 30/11/2017


José Mª Sanz

Division of Agrifood and Processes


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